Welcome!
Welcome to the Vincent Coates Foundation Mass Spectrometry Laboratory.
The laboratory is named in honor of a generous gift from Vincent and Stella Coates, given through the Stanford School of Medicine to support the mass spec & proteomics facility as a shared core resource. It is a Bio-X core facility, embodying the Bio-X spirit of interdisciplinary communication and collaboration. It is also partially supported as the Proteomics Shared Resource of the Stanford Cancer Institute. The Dean of Research provides oversight and support to keep the laboratory's expertise and support available to researchers throughout Stanford University & Medical Center.
Beyond making available state-of-the-art, user-friendly facilities and services, the laboratory enables education, methods development, and new applications development, designed to meet the rapidly evolving needs of researchers. Due to the essential information that mass spectrometry provides to researchers in the fields of the physical and life sciences, medicine, and engineering, the laboratory serves as an “intellectual watering hole” at the crossroads of diverse disciplines.
We have numerous instruments in operation: one GC-MS, a MALDI-TOF, and many LC-MS systems, including a single quad, four triple quads, four quadrupole-Orbitraps, and two Orbitrap tribrids. Software resources include instrument-specific packages Xcalibur, MassLynx, Mass Hunter; proteomics software Byonic, Mascot, Proteome Discoverer; and other tools including LCquan, QuanLynx, OpenLynx, MetaboLynx, Spectral Works.
Routine mass spec and proteomic services include molecular weight determination from small molecules to intact proteins, high resolution MS, bottom-up proteomics and more. Please contact SUMS to discuss custom work such as complex proteomic analysis, relative and targeted quantitation, drug discovery support, de novo peptide sequencing, new application development, and other projects.
Types of Service and Analysis Offered by SUMS:
Allis Chien, PhD | SUMS Director
Office (Bass 026): (650) 723-0710
Email: allis at stanford.edu
Ryan Leib, PhD | SUMS Director of Research
Office (Bass 024): (650) 725-9769
Email: allis at stanford.edu
Fang Liu, PhD | SUMS Director of Proteomics
Office (Bass 024): (650) 725-9769
Email: fliu7 at stanford.edu
William Lee | Accounting Associate
Office (Bass 024): (650) 725-9769
Email: wlee2 at stanford.edu
| Name | Role | Slack Username | Email (@stanford.edu) | Location | ||||
| Ludmila Alexandrova, PhD | Drug discovery support, PK, Metabolite ID | ludmila_alexandrova | ludmilaa@ | Bass 024 | ||||
| Megan Danielewicz, PhD | Metaolomics, Quantitative MS | m3g4n | m3g4n@ | Bass 024 | ||||
| Karolina Krasinska, MS | Quantitative MS | karolina_krasinska | krasin@ | Bass 024 | ||||
| Juan Pablo Galindo Lazo, MS | Proteomics | fliu7 | fliu7@ | Bass 024 | ||||
| Vivian Lu, PhD | Chemical Imaging | xlu50020 | xlu50020@ | Bass 024 | ||||
| Garvey Mckenzie, PhD | Proteomics | gmcken1 | gmcken1@ | Bass 024 | ||||
| Theresa McLaughlin, MS | Lab Manager, Open access, HRMS, intact protein | theresa_mclaughlin | tmcl@ | Bass 024 | ||||
| Casey Powers, PhD | Education, Proteomics | casey_schmidt | capowers@ | Bass 024 |
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Location |
Hours - Contact SUMS to make arrangements. |
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SUMS, 327 Campus Drive Room: 024 Stanford University, Stanford, CA 94305-4401 Phone: (650) 725-9769 Email: spectrometry@stanford.edu |
9 a.m. - 5 p.m., Monday to Friday 24/7 access for trained Open Access users
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Click to view SUMS location on Stanford Campus Map
In accordance with Dean's office policy: If work done with SUMS produces data in a publication, you must acknowledge us ("Vincent Coates Foundation Mass Spectrometry Laboratory, Stanford University Mass Spectrometry") in the publication. Further, if SUMS staff provide significant experimental design, data interpretation, or other intellectual contribution (as evaluated by the PI), then it is expected that these individuals will be coauthors on the publication.
In addition, please acknowledge the following:
Stanford Cancer Institute: As a Stanford Cancer Institute Shared Resource, our lab receives grant support from the National Cancer Institute, which should be acknowledged in all publications containing data collected at SUMS. The following statement is suggested: “This work was supported in part by NIH P30 CA124435 utilizing the Stanford Cancer Institute Proteomics/Mass Spectrometry Shared Resource.”
The NIH requires that all publications containing data collected on our Shared Instrumentation Grant (SIG) Program funded instruments acknowledge NIH grant support.
Orbi Elite: "This work utilized the Thermo LTQ-Orbitrap mass spectrometer system (RRID:SCR_018694) that was purchased with funding from National Institutes of Health Shared Instrumentation Grant S10RR027425."
Xevo TQ-XS: "This work utilized the Waters Xevo TQ-XS mass spectrometer system (RRID:SCR_018510) that was purchased with funding from National Institutes of Health Shared Instrumentation Grant S10OD026962."
Orbi Eclipse: "This work utilized the Thermo Orbitrap Eclipse nanoLC/MS system (RRID:SCR_022212) that was purchased with funding from National Institutes of Health Shared Instrumentation Grant 1S10OD030473."
6495 Triple Quad: "This work utilized the Agilent 6495 Triple Quadrupole LC/MS system (RRID:SCR_023937) that was purchased with funding from National Institutes of Health Shared Instrumentation Grant 1S10OD034374."
RRIDs for non-NIH funded instruments:
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Allis Chien, Ph.D. |
Director
|
650.723.0710
|
allis at stanford.edu
|
Bass 026
|
| Ryan Leib, Ph.D. |
Director of Research
|
650.725.9769
|
rdleib at stanford.edu
|
Bass 026
|
| Fang Liu, Ph.D. |
Director of Proteomics
|
650.725.9769
|
fliu7 at stanford.edu
|
Bass 024
|
| Theresa McLaughlin, M.S |
Lab Manager, Open Access
|
650.725.9769
|
tmcl at stanford.edu
|
Bass 024
|
| William Lee |
Finance
|
650.725.9759
|
wlee2 at stanford.edu
|
Bass 024
|
