Human Immune Monitoring Center

The Human Immune Monitoring Center (HIMC) is designed to be a comprehensive source for immune monitoring services for clinical and translational studies.  We perform:

Immunoassays:  Luminex cytokine arrays, MesoScale Discovery assays

Mass Cytometry (CyTOF):  Immunophenotyping, Intracellular cytokines, Phospho-epitopes

Flow Cytometry:  Immunophenotyping, Intracellular cytokines, Phospho-epitopes

Genomics:  RNA/DNA extractions, Microarrays, Microfluidic qPCR arrays, Targeted RNAseq

BioBanking:  Serum, Plasma, PBMC, and Tissue processing; Sample banking and retrieval

Parallel coordinates view of Luminex cytokine data:                             SPADE analysis of CyTOF data:

  

Goals of the HIMC include:

1. To provide standardized, state-of-the art immune monitoring assays at the RNA, protein, and cellular level. These are assays that have already been validated in the HIMC.
2. To test and develop new technologies for immune monitoring. We are always developing new assays in the above areas, as well as testing new potential immune monitoring platforms.
3. To efficiently archive, report, and mine data from immune monitoring studies, so as to increase the value of the data and to assist in biomarker discovery. The HIMC uses Stanford Data Miner for integration of data from the standard HIMC assays, along with de-identified clinical and demographic data. One year after release of results to an investigator, data will be released for all users of the HIMC to access, unless appealed by the investigator for reasons of still-pending publication.

The HIMC was developed in 2007 by the Institute for Immunity, Transplantation, and Infection (Mark Davis, Ph.D., director) in conjunction with the Center for Clinical Immunology (C. Garrison Fathman, founder).  Our Faculty Advisor is Mark Davis.

Name

Role

Phone

Email

Location

Yael Rosenberg-Hasson

Technical Director, Immunoassay Mgr

650-723-4984

yaelhr at stanford.edu

Mike Leipold

Mass Cytometry (CyTOF) Manager

650-723-4984

mleipold at stanford.edu

299 Campus Dr. Fairchild Science Bldg; Rm D033

1651 Page Mill Road, Palo Alto, CA 94304; Rm 107

Location

Building

Room

Hours

Location

Immunoassay & Cell Analysis Lab     

1651 Page Mill Road,  

9 AM - 5 PM     

Genomics Lab

1651 Page Mill Road,

107

8 AM - 5 PM

Mass Cytometry & Flow

299 Campus Dr. Fairchild Science Bldg

D033

9 AM - 5 PM 

http://goo.gl/maps/swj8g