Human Immune Monitoring Center


Welcome to the HIMC - Human Immune Monitoring Center

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HIMC:  A one-stop shop for immune monitoring services.                         What we can measure in the immune system.

Overview of Services


The Human Immune Monitoring Center (HIMC) is designed to be a comprehensive source for immune monitoring services for clinical and translational studies.  We perform:


Immunoassays:  Luminex cytokine arrays, MesoScale Discovery assays

Mass Cytometry (CyTOF):  Immunophenotyping, Intracellular cytokines, Phospho-epitopes

Flow Cytometry:  Immunophenotyping, Intracellular cytokines, Phospho-epitopes

Genomics:  RNA/DNA extractions, Microarrays, Microfluidic qPCR arrays, Targeted RNAseq

BioBanking:  Serum, Plasma, PBMC, and Tissue processing; Sample banking and retrieval


Parallel coordinates view of Luminex cytokine data:                             SPADE analysis of CyTOF data:


Goals of the HIMC include:

  1. To provide standardized, state-of-the art immune monitoring assays at the RNA, protein, and cellular level. These are assays that have already been validated in the HIMC.
  2. To test and develop new technologies for immune monitoring. We are always developing new assays in the above areas, as well as testing new potential immune monitoring platforms.
  3. To efficiently archive, report, and mine data from immune monitoring studies, so as to increase the value of the data and to assist in biomarker discovery. The HIMC uses Stanford Data Miner for integration of data from the standard HIMC assays, along with de-identified clinical and demographic data. One year after release of results to an investigator, data will be released for all users of the HIMC to access, unless appealed by the investigator for reasons of still-pending publication.

The HIMC was developed in 2007 by the Institute for Immunity, Transplantation, and Infection (Mark Davis, Ph.D., director) in conjunction with the Center for Clinical Immunology (C. Garrison Fathman, founder).  Our Faculty Advisor is Mark Davis.


Getting Started


  • Stanford Users:  LOGIN or REGISTER for an iLab account using valid Stanford credentials (SUNet ID).



Holden Maecker, PhD | Facility Director

Office (Rm D039, Fairchild Building):  (650) 723-1671

Email:  maecker at










Yael Rosenberg-Hasson

Technical Director, Immunoassay Mgr


yaelhr at

1651 Page Mill Road, Palo Alto, CA 94304; Rm 360

Mike Leipold

Mass Cytometry (CyTOF) Manager


mleipold at

299 Campus Dr. Fairchild Science Bldg; Rm D033

Xuhuai Ji Genomics Manager 650-723-5050 xuhuai.ji at

1651 Page Mill Road, Palo Alto, CA 94304; Rm 107



Locations and Hours of Operation 








Immunoassay & Cell Analysis Lab     

1651 Page Mill Road,  


9 AM - 5 PM     

Genomics Lab

1651 Page Mill Road,


8 AM - 5 PM

Mass Cytometry & Flow

299 Campus Dr. Fairchild Science Bldg


9 AM - 5 PM


Links and Resources


Publication Acknowledgement 

As with all Stanford Service Centers, credit must be given to Human Immune Monitoring Center (HIMC) for data that results in a publication. If the work done at HIMC produces data resulting in a figure in a publication, you are required to acknowledge HIMC in the publication. Further, if HIMC staff members provided significant experimental design, data interpretation, or other intellectual contribution (as evaluated by the PI), then it is expected that these individuals will be coauthors on the publication.

One of our CyTOFs was purchased with funds from a NIH S10 Shared Instrumentation Grant (S10RR027431-01).  Please acknowledge this grant in your papers using CyTOF data.


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Name Role Phone Email Location
Holden Maecker, PhD
Fairchild Sci Bldg, Rm D039, 299 Campus Drive, Stanford, California 94305-5124
Debra Panasuk
Finance Manager
Biomedical Innovations Building, 240 Pasteur Dr., Palo Alto, CA 94304-5422

Service Price List

Search available services: View: by category alphabetically
Flow Cytometry (8)
Immuno Assays (5)
Molecular and Genomic Assays (21)
Other Services and Fees (3)


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